Aldosterone Receptor Antagonist Diuretics
Valsartan is an angiotensin ii type 1 at 1 receptor antagonist ie angiotensin ii receptor blocker arb.
Aldosterone receptor antagonist diuretics. An antimineralocorticoid mcra or an aldosterone antagonist is a diuretic drug which antagonizes the action of aldosterone at mineralocorticoid receptors. General pharmacology renal handling of sodium and water. To understand the action of diuretics it is first necessary to review how the kidney filters fluid and forms. A vasopressin receptor antagonist vra is an agent that interferes with action at the vasopressin receptors.
Most commonly vras are used in the treatment of. Angiotensin receptor blockers arbs are reasonable first line therapy for patients with mild to moderate heart failure symptoms and left ventricular. Aldosterone antagonist therapy for adults with heart failure and preserved systolic function topcat. Research news 2019 news.
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